Doctors in Europe and the US have conflicting opinions about the pace of liver fibrosis in HIV-positive men with hepatitis C infection. In a study published in Clinical Infectious Diseases, European investigators showed that the pace of liver fibrosis slowed after the acute phase of infection. However, doctors from the US have published contrasting findings, showing that fibrosis continued to worsen with longer duration of co-infection.
The discrepancy between the studies could be a result of the methods used to evaluate liver fibrosis. The European investigators used Fibroscan, evaluating liver stiffness, whereas patients in the US study were monitored using liver biopsies.