WASHINGTON, D.C. — Patients with hepatitis C virus infection and
alcohol-use disorder had an increased risk for mortality by
liver-related causes compared with those with an alcohol-use disorder,
but not hepatitis C virus, according to data presented at ICAAC 2014.
In a longitudinal study, researchers collected data and conducted tests, such as liver function tests, in 819 patients with alcohol-use disorder between 1999 and 2010 to determine if hepatitis C virus
(HCV) infection played a role in causing mortality among patients
receiving treatment for alcohol-use disorder. Among all the patients,
129 were positive for HCV, 690 patients were HCV-negative. The median
follow-up was 3.8 years.
“HCV infection in patients with [alcohol-use disorder] is associated
with an increased risk of overall and liver-related mortality,” the
researchers wrote. “The irruption of innovative anti-HCV therapies may
have an impact in the survival of these patients.”