Note: Higher spontaneous clearance rates have been known for some time based on patient characteristics. I wonder about the true number of people who have been exposed to HCV, cleared the virus and have not been factored into the estimated prevalence of HCV. Alan
Up to 30% to 40% of patients naturally clear infection of hepatitis C virus (HCV), which is “substantially higher” than previous estimates, according to a recent article in the International Journal of Infectious Diseases.
“Having an accurate and precise estimate of HCV clearance rate is important for HCV response, and will inform HCV treatment in early infection, planning of health services provision, and estimation and projections of HCV chronic infections and disease burden,” wrote authors led by Laith J. Abu-Raddad, PhD, Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Doha, Qatar.
Earlier studies have pegged the number of people who naturally beat HCV between 10% and 15%. More recent longitudinal studies have yielded a wide range of clearance rates between 0% and 57% from 6 to 48 months post-infection, with the best estimate of approximately 25% at 16.5 weeks.