Title: Risk factors, mortality, and cardiovascular outcomes in patients with type 2 diabetes—A. Rawshani, et. al.
Study Aims and Results: The aim of the study was to find out if the risk of death in people with type 2 diabetes could be altered. The Swedish National Diabetes Register study included 271,174 patients with type 2 diabetes patients and matched them with 1,355,870 controls on the basis of age, sex and county. The cohort prospective study followed the patients for a median of 5.7 years. Prospective studies follow patients from the beginning of a study until the conclusion of the study. They assessed the patients by age and according to five risk factors: elevated glycated hemoglobin level (hemoglobin A1c), cholesterol level, albuminuria (a symptom of kidney disease), smoking and elevated blood pressure. The study evaluated certain outcomes—death, heart attack, stroke and hospitalization for heart failure. The study used the Cox Proportional Hazards Regression Analysis to predict the risk of death. The Cox Analysis is a well-known and widely used model to predict future disease outcomes.
Conclusions: The people with diabetes in the study who had the 5 risk-factors within the target ranges had little or no excess risk of death, heart attack, or stroke compared to the general population.
Editorial Comments: Type 2 diabetes is an extrahepatic manifestation of hepatitis C (HCV). It is also a disease that can lead to an early death and it can cause severe diabetes-related outcomes if it is not well-controlled.
The strength of the current study is that it is a prospective study that followed people over time and it was a large population-based study. This is very positive news for people with type 2 diabetes. It should also encourage people to make lifestyle changes to keep their blood sugar levels within healthy ranges and work to reduce the other 5 risk factors to increase the chances for a longer and healthier life.Share This Page