Title: Abstract: #203 Chronic Hepatitis C Infection Elicits a Poly-Functional T Cell Immune Response at the Maternal/Fetal Interface to Limit Vertical Transmission – Matthew A. Burchill, et al. By Lucinda Porter, RN
Approximately one to three percent of pregnant women in the US are infected with HCV. Despite this, the rate of vertical transmission between mother and fetus is quite low at four to eight percent. Researchers wanted to know why.
Conclusion: Looking at mother-child pairs with and without HCV, they found an aspect of fetal immunity by identifying HCV-specific T cells at the maternal/fetal interface. Further, the T cell responses at the maternal/fetal interface are highly active in patients with active HCV infection. Researchers speculated as to whether in the future this understanding can lead to reduced transmission rates of not only HCV, but also of hepatitis B.
Editorial Comments: This is very exciting. Few things break my heart more than hearing about women who learn that their child has hepatitis C because of vertical transmission.Share This Page