SEATTLE — A small pilot study of hepatitis C treatment in pregnant women found that that the treatment was effective in achieving hepatitis C cure and identified no safety concerns associated with treatment, according to findings presented at CROI.
Although guidelines from the Infectious Diseases Society of America and the American Association for the Study of Liver Diseases recommend that all women be tested for HCV at the initiation of prenatal care, treatment during pregnancy is not recommended. However, the rate of HCV infection among pregnant women is rising in the United States, increasing the risk for perinatal transmission, according to Catherine A. Chappell, MD, MSc, assistant professor of obstetrics, gynecology and reproductive sciences at the University of Pittsburgh, and colleagues.
“Over the last decade there has been about a twofold increase in hepatitis C among pregnant women delivering at my hospital,” Chappell said in a news conference. “That’s particularly important because of the babies that are delivered from those women, about one in 20 of them will go on to have perinatal hepatitis C infection.”