Article: Evaluation of the Xpert HCV Viral Load Finger-Stick Point-of-Care Assay – F.M.J. Lamoury, et. al.
Source: The Journal of Infectious Diseases, Volume 217, Issue 12, 25 May 2018, Pages 1889–1896, https://doi.org/10.1093/infdis/jiy114
Study Aims and Results: The finger-stick viral load assay results can be given in 1 hour, allowing for a single visit HCV diagnosis after a positive HCV antibody result. The aim was to test the reliability of an HCV RNA (viral load) finger-stick assay compared to the blood draw assay. There were two arms in the study—an HCV viral load negative group of 125 people (comparator arm) and an HCV positive viral load group of 85 people (study arm).
The study tested the sensitivity (to correctly identify those with the disease) and specificity (to correctly identify those without the disease) by blood draw compared to finger prick.
Conclusions: The Xpert HCV Viral Load Finger-Stick Point-of-Care Assay is a reliable HCV viral load assay that provides 100% accuracy.
Editorial Comments: Currently, people who test HCV antibody positive have to return for an HCV viral load test or if they have a blood draw for a viral load test they have to return later for the results. If a patient has to return for the results, it can lead to patient anxiety, and patients may be lost to follow-up. The Point-of-Care finger stick diagnostic test will help to diagnose active HCV infection immediately, eliminate the need for a blood draw, provide immediate medical care, counseling, and follow-up care. Finally, it will be another tool to help eliminate HCV.Share This Page