Patients coinfected with HIV and hepatitis C may experience a reduction in abnormal liver enzymes and an overall improvement in liver function with increased consumption of coffee and chocolate, a study determined.
“Our results provide the first evidence that daily chocolate intake and, more generally, polyphenol rich food intake, may contribute to decreased AST [aspartate aminotransferase] and ALT [alanine aminotransferase] levels and potentially improve liver function in HIV-HCV coinfected patients,” the researchers wrote. “They also suggest that polyphenols contained in coffee, but also in cocoa, can be involved in the causal process, which leads to reduced inflammation.”
Polyphenols contained in coffee, but also in cocoa, may contribute to
decrease liver enzymes levels, but these results need to be confirmed by
further experimental and observational research.
Patients coinfected with HIV and HCV who reported eating chocolate
daily and drinking three or more cups of coffee a day had lower levels
of ALT and AST than those who consumed fewer polyphenol-rich foods in a
Researchers evaluated data collected from 990 adult patients coinfected with HCV and HIV
enrolled in the ANRS CO13 HEPAVIH prospective cohort study. Patients
with cirrhosis had follow-up visits every 6 months, while noncirrhotic
participants had annual visits, with liver biochemistry assessed at each
visit. Participants also responded to annual self-administered
questionnaires regarding sociodemographic status and dietary and drug