This is an interesting study from South Korea that
details the demographics and risk factors for HCV. -AF
Abstract:Clinical and epidemiological features of hepatitis C virus infection in South Korea: A prospective, multicenter cohort study.
Seong MH, Kil H, Kim YS, Bae SH, Lee YJ, Lee HC, Kang BH, Jeong SH.
Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
The epidemiological and clinical features of hepatitis C virus (HCV)
infection in South Korea were examined in a prospective, multicenter
cohort study that included 1,173 adult patients with positive results
for anti-HCV antibody who completed a questionnaire survey on the risk
factors for HCV infection from January 2007 to December 2011 at five
The HCV cohort had a mean age of 55.4 years with
48.3% men, and diagnostic categories of acute hepatitis (n = 63, 5.3%),
past infection (n = 37, 3.2%), chronic hepatitis (n = 777, 66.2%),
cirrhosis of the liver (n = 179, 15.3%), and hepatocellular carcinoma
(n = 117, 10.0%). The major HCV genotypes were genotype 1 (52.7%) and
genotype 2 (45.3%). Liver biopsy was performed in 301 patients (25.7%),
and 42.8% of the subjects received antiviral therapy against HCV. The
behavioral risk factors possibly related to HCV infection were
intravenous drug use (5%), needle stick injury (7%), blood transfusion
before 1995 (19%), sexual relationship with more than three partners
(28%), piercings (35%), tattoos (36%), surgery (43%), acupuncture (83%),
diagnostic endoscopy (85%), and dental procedures (93%).
intravenous drug use, needle stick injury, transfusion before 1995, and
tattoos were the independent risk factors of HCV infection. J Med.
Virol. 85:1724-1733, 2013. © 2013 Wiley Periodicals, Inc.
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