NEW YORK — Patients with hepatitis C virus infection often showed signs
of mild liver disease when diagnosed with HCV-associated B-cell
non-Hodgkin’s lymphoma, according to data presented at the AASLD/EASL
Special Conference on Hepatitis C.
Eighty-four patients with HCV-associated non-Hodgkin’s lymphoma
(HCV-NHL) were evaluated to determine liver disease stages. The cohort
was primarily male (73%), white (62%) and had HCV genotype 1 (64%) or
genotype 2 infection (22%). Patients who had previously achieved
sustained virologic response through antiviral therapy (AVT) were
compared with patients who had not reached SVR.
Research indicated that previous health care providers of patients with
HCV did not recommend AVT in 47% of cases because advanced liver disease
at HCV diagnosis was not prominent. Forty-two percent of all patients
were not afforded previous care for HCV since HCV and NHL were diagnosed
simultaneously. Researchers did not determine any predictors for
developing HCV-NHL despite some patients achieving previous SVR.