FARMINGTON, Conn. — With the
introduction of interferon free therapies, it is possible that the
hepatitis C infection may be cured or even eradicated within the next 10
to 20 years.
BroadcastMed, Inc. and UAB Medicine present Brendan
McGuire, MD, and his colleagues at the University of Alabama at
Birmingham with their review of the changing landscape for the treatment
of the hepatitis C virus (HCV).
View their presentation on the UAB MD Learning Channel, http://learnmd.uabmedicine.org/videos/overview-of-hepatitis-c.
It includes an overview of hepatitis C, a discussion on the
epidemiology of the disease, and an exploration of complications in HCV
patients, possible liver transplantation, and the current and future
roles of therapies in treating and possibly curing the disease.
The way we treat medical conditions is
constantly evolving. From new ways of distributing medical information
to new drugs and therapies. Alexander Kuo, MD joins David Granet, M.D.,
F.A.C.S., F.A.A.P. to discuss how he uses shared medical appointments to
give his patients in-depth care. Dr. Kuo also highlights new treatments
for Hepatitis C.
A study was recently released that reviewed data from the National
Health and Nutrition Examination Surveys from 2003 to 2010 to
understand the percentage of people with hepatitis C (HCV) aged 40 yo
or older who were initially infected (HCV antibody positive) and who
subsequently became HCV undetectable (resolved) compared to those who
continued to test for HCV RNA (chronic). It was found that 75.3% of
the people who tested HCV antibody positive did not resolve the initial
An important finding of the study was that 91.1% of non-Hispanic Blacks did not resolve acute infection compared to non-Hispanic Whites.
One of the most alarming findings of this study
was that in people who had abnormal liver enzymes—alanine
aminotransferase—ALT (56.5 %) and aspartate aminotransferase—AST
(71.8 %)—only 35.3% had been diagnosed. As usual, more education is
needed among medical providers and patients.
Racial Disparities in the Proportion of Current, Unresolved Hepatitis C Virus Infections in the United States, 2003-2010. Liu G1, Holmberg SD, Kamili S, Xu F. Dig Dis Sci. 2014 Feb 27. [Epub ahead of print]
Nearly half of adults infected with hepatitis C sought testing only
after experiencing the clinical indications of liver disease, according
to the CDC.
“Chronic hepatitis C virus (HCV) infection causes substantial
morbidity and mortality in the United States,” researchers wrote in Morbidity and Mortality Weekly Report. “Testing and treatment of asymptomatic persons might avert progression to more advanced disease.”
Be Sure to Check Out this New HCSP Fact Sheet by Alan Franciscus
There have been studies that found that 30 to 70%
people with HCV have insulin resistance or diabetes.
One study found that people with HCV who are age 40
and older were nearly four times more likely to have
diabetes. The exact cause of diabetes in people with
HCV is not completely understood, but it believed that
the hepatitis C virus may interfere with the way that glucose
is metabolized by the liver. Due to the high rates
of diabetes in the HCV population some experts believe
that people with HCV should be routinely screened for